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DATURA

Determination of Adequate TUberculosis Regimen in Adults and adolescents hospitalised with HIV-associated severe immune suppression – NCT04738812

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Newsletter for spring 2025

Posted on 22/07/2025 by rhe001

Please find the latest newsletter for 2025 here.

This entry was posted in other by rhe001. Bookmark the permalink.

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DATURA – a clinical trial

DATURA addresses people who are co-infected with TB and HIV. It is a research project that aims to assess whether an intensified initial TB treatment could increase survival in hospitalised, HIV-infected adults and adolescents compared to the standard TB treatment regime.

DATURA is registered in ClinicalTrials.gov : NCT04738812

  • Learn more key facts about TB & HIV – 2 often inter-linked global health challenges 
  • Why is DATURA undertaking this research?
  • DATURA Work Packages

Who is who in DATURA?

  • List of participants by role in project
  • Clinical sites
  • Participants listed by Work Project
  • Partner Institutions

Governance meetings

  • Project Executive meeting: 1 meeting every 3 months. Next on December 20th, 2022
  • Project Steering Committee: 1 meeting per year. Next on November or December, 2022
  • Data and Safety Monitoring Board meeting: the first meeting after the start of inclusions will be on October 24th, 2022

 

Important DATURA dates:

  • Mozambique participated as a trial site by 2024, with first patient inclusion in February 15th, 2024
  • The European and Developing Countries Clinical Trials Partnership (EDCTP)signed the Grant 14 April 2020.
  • Official starting date of the project period is 1 May 2020. The project will last for 54 months from this date.
  • DATURA kick-off 14-15 Sept. 2020
  • First participant enrolled on April 21st, 2022.
  • All African sites recruiting by August 2022.
  • EDCTP grant extended for an additional 14 months until December 2025.

TB Day

24 March – mark your calendar!

HIV Day

1 December – mark your calendar!

Recent Posts

  • Newsletter for spring 2025
  • Finalization of Participant Enrollment
  • First joint Project Steering Committee and Data and Safety Monitoring Board Meeting in 7-9 July 2024.

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