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DATURA

Determination of Adequate TUberculosis Regimen in Adults and adolescents hospitalised with HIV-associated severe immune suppression – NCT04738812

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    • More about DATURA
    • DATURA project governance
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      • Cambodia
      • Cameroon
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  • Participants
    • Bindiya Meggi
    • Boubacar Djelo Diallo
    • Charles Kouanfack
    • Conrad K. Muzoora
    • Didier Laureillard
    • Eric Dailly
    • Eric-Walter Pefura
    • François-Xavier Blanc
    • Jean-Pierre Molès
    • John Tembo
    • Kondwelani John Mateyo
    • Maryline Bonnet
    • Nicolas Nagot
    • Ricky Heggheim
    • Suilanji Sivile
    • Sven Gudmund Hindraker
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Partners

Partner Institutions:


Institut national de la santé et de la recherche médicale, INSERM (UMR 1058), Montpellier, France

 


University of Bergen, Norway

 

Centre Hospitalier Universitaire de Nantes, France

 

 

Institut de Recherche pour le Développement (IRD), France

 

 

Médecins Sans Frontières –Epicentre, France

 

Hôpital national Ignace Deen, Conakry, GUINEA

Central Hospital of Yaoundé, CAMEROON

 

 

 

University Teaching Hospital, Lusaka, ZAMBIA

 

 

 

 

Mbarara University of Science and Technology, UGANDA

 

 

Institut Pasteur du Cambodge, Phnom Penh, CAMBODGE

 

 

National Centre for HIV/AIDS Dermatology and STDs, Phnom Penh, CAMBODIA

 

 

Instituto Nacional de Saúde, Maputo, Mozambique

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DATURA – a clinical trial

DATURA addresses people who are co-infected with TB and HIV. It is a research project that aims to assess whether an intensified initial TB treatment could increase survival in hospitalised, HIV-infected adults and adolescents compared to the standard TB treatment regime.

DATURA is registered in ClinicalTrials.gov : NCT04738812

  • Learn more key facts about TB & HIV – 2 often inter-linked global health challenges 
  • Why is DATURA undertaking this research?
  • DATURA Work Packages

Who is who in DATURA?

  • List of participants by role in project
  • Clinical sites
  • Participants listed by Work Project
  • Partner Institutions

Governance meetings

  • Project Executive meeting: 1 meeting every 3 months. Next on December 20th, 2022
  • Project Steering Committee: 1 meeting per year. Next on November or December, 2022
  • Data and Safety Monitoring Board meeting: the first meeting after the start of inclusions will be on October 24th, 2022

 

Important DATURA dates:

  • Mozambique participated as a trial site by 2024, with first patient inclusion in February 15th, 2024
  • The European and Developing Countries Clinical Trials Partnership (EDCTP)signed the Grant 14 April 2020.
  • Official starting date of the project period is 1 May 2020. The project will last for 54 months from this date.
  • DATURA kick-off 14-15 Sept. 2020
  • First participant enrolled on April 21st, 2022.
  • All African sites recruiting by August 2022.
  • EDCTP grant extended for an additional 14 months until December 2025.

TB Day

24 March – mark your calendar!

HIV Day

1 December – mark your calendar!

Recent Posts

  • Finalization of Participant Enrollment
  • First joint Project Steering Committee and Data and Safety Monitoring Board Meeting in 7-9 July 2024.
  • Newsletter for spring 2024

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